Diabetes and pre-diabetes are associated with cardiovascular risk factors and carotid/femoral intima-media thickness independently of markers of insulin resistance and adiposity

Diabetes and pre-diabetes are associated with cardiovascular risk factors and carotid/femoral intima-media thickness independently of markers of insulin resistance and adiposity

Bovet Pascal, Faeh David, Paccaud Fred, William Julita, Yerly Patrick
Cardiovascular Diabetology 2007, 6:32
Published: October 2007
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Abbreviations
BMI: body mass index; BP: blood pressure; CRP: C-reactive protein. CVD: cardiovascular disease; DM: diabetes mellitus; FBG: fasting blood glucose; HDL-C: high-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; IFG: impaired fasting glucose; IGT: impaired glucose tolerance; IMT: intimamedia thickness; LDL-C: low density lipoprotein cholesterol; OGTT: oral glucose tolerance test; 2hBG: 2-hour postload blood glucose

Competing interests
The author(s) declare that they have no competing interests.

Authors' contributions
DF led the analysis of the data and the write up of the manuscript. JW coordinated several aspects of the survey and reviewed the manuscript. PY conducted ultrasonography on all participants and reviewed the manuscript. FP assisted in the interpretation of data and reviewed the manuscript. PB led the organization of the survey, assisted with the analysis and interpretation of the data and with the write up of the manuscript. All authors read and approved the final manuscript.

Acknowledgements
We would like to thank Professors Luc Tappy (Lausanne) and Nigel Unwin (Newcastle) for helpful comments on previous versions of the manuscript. We also thank the survey officers, particularly George Madeleine, Bharathi Viswanathan and Vanessa Lafortune as well as all the participants to the survey. Partial funding came from the Ministry of Health, Republic of Seychelles; the Institute of Social and Preventive Medicine. University of Lausanne, Switzerland: the Department of Physiology, University of Lausanne, Switzerland; the Institute of Clinical Chemistry and Hematology, St. Gallen, Switzerland; the World Health Organization, Brazzaville; and the Seychelles Marketing Board, Air Seychelles, and SkyChef Ltd (Seychelles).

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