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Friday, 09 May, 2008



Hot Topic
Study Of Lung Damage In Babies With Congenital Heart Disease
11 March 2008
Trying to understand and stop the collateral lung damage that can occur in babies with congenital heart disease is the focus of a new study. When a baby's heart defect results in too much blood in the lungs, more blood vessels are made, apparently to handle the increased volume, then new blood vessel growth is abruptly halted.

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A selection of must-have articles

Graph

Mid-term echocardiographic follow up of left ventricular function with permanent right ventricular pacing in pediatric patients with and without structural heart disease
Chronic right ventricular apical pacing may have detrimental effect on left ventricular function and may promote to heart failure in adult patients with left ventricular dysfunction.

VA-ECMO circuit model

Factors influencing the outcome of paediatric cardiac surgical patients during extracorporeal circulatory support
We assessed the outcome of children who had extracorporeal membrane oxygenation (ECMO) following repair of congenital cardiac defects (CCD) and identified the risk factors associated with hospital mortality.

Tubular hypoplasia

Aortic obstruction: anatomy and echocardiography
Echocardiography is a valuable non-invasive technique for identifying the site and type of aortic obstruction.

Keeping you up to date with the latest clinical trial information

Pro-Calcitonin Levels Following Pediatric Cardiac Surgery

Emory University find out the PCT response to heart surgery in children by taking blood before surgery and each day for four days after surgery. These blood draws will help us figure out the typical PCT response, the normal increase in PCT after heart surgery, and when the PCT level returns to baseline.

Second, they hope to determine the accuracy of PCT as a marker of infection.

The hypothesis is that Procalcitonin is superior to other currently used markers of infection and will prove to be a clinically useful tool for evaluation of infection in children following cardiac surgery.

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Keeping you up to date with the latest clinical trial information

Pediatric Lead Extractability and Survival Evaluation (PLEASE)

The Children's Hospital Boston, Medtronic and the Guidant Corporation are conducting a randomized, prospective clinical trial comparing 2 different models of implantable cardioverter defibrillator (ICD) leads in children and patients with congenital heart disease. ICD lead survival in this patient group is particularly suboptimal, and lead extraction is technically difficult and carries a substantial morbidity risk. Recently, improved ICD lead designs have been released and are currently being utilized in patients. The main aim of the study is to determine if either type of lead performs better in terms of implantation electrical characteristics, long-term survival without breaking, and ease of extractability.

Related Articles

Journal Watch
Selected headlines from the top Cardiology journals

Practicing paramedics cannot generate or estimate safe endotracheal tube cuff pressure using standard techniques

In a study to determine the ability of paramedics to generate or estimate safe endotracheal tube cuff pressure every paramedic inflated the cuff above the safe limit, and 87% could not detect an overinflated cuff by palpation of the pilot balloon. Prehosp Emerg Care 2007; Jul-Sep;11(3):307-11

Guidelines Watch
A round up of the latest Clinical Guidelines from the National Guideline Clearinghouse (NGC)

ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging: A report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (ACC/AHA/ASNC Committee to revise the 1995 guidelines for the clinical use of cardiac radionuclide imaging)
American College of Cardiology Foundation - Medical Specialty Society American Heart Association - Professional Association American Society of Nuclear Cardiology - Professional Association. 1995 Feb (revised 2003 Aug). 69 pages. NGC:003137

Revised indications for the use of palivizumab and respiratory syncytial virus immune globulin intravenous for the prevention of respiratory syncytial virus infections
American Academy of Pediatrics - Medical Specialty Society. 2003 Dec. 5 pages. NGC:003325


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