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From The ACC 07 Scientific Sessions
A Percutaneous Approach to Treat Moderate to Severe Mitral Valve Regurgitation Using A Non-Surgical Repair System
Presentation Number: 2406-13
March 25
Trial Team
A team led by Dr Karl-Heinz Kuck, cardiology director at the Allgemeines Krankenhaus St Georg, Hamburg, Germany evaluated the safety and feasibility of the MONARC system in patients with moderate-to-severe mitral regurgitation.
The Procedure
The MONARC system consists of two stent-like anchors, a spring bridge that connects the anchors, and a biodegradable element within the bridge. Using a jugular approach, the catheter-mounted device is threaded through the coronary sinus and the anchors positioned such that the metal bridge surrounds a significant portion of the mitral valve annulus. Over a period of several weeks the bridge shortens by more that 20%, creating tension around the mitral valve allowing the leaflets and valve structures to reshape.
Preliminary Results
Data was presented on 36 patients, 32 of which received successful MONARC implants without serious complications. Dr Kuck reported that the mean MR gradually decreased over 180 days.
Three months after implantation, ECG showed significant improvement in mitral tregurgitation in most patients. Reduction would be expected in the first 6 weeks post-implantation due to the bridge physically shortening and Dr Kuck further added that the continued shortening after 6 weeks indicated that the system drove greater response.
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