Articles

Adherence to Lipid Lowering - Growing Clinical Challenge

Patients with low adherence are also responsible for substantially greater health care costs than are patients with good adherence. Even accounting...

Ankle blood pressure as a predictor of total and cardiovascular mortality

BackgroundThere are several established procedures for estimating subclinical atherosclerotic changes in human arteries. Increased carotid...

Aspirin and Statins to Decrease Risks of Cardiovascular Disease - The Need for Wider Utilization

With regard to statins, in basic research these drugs decrease total and low-density lipoprotein (LDL) cholesterol as well as trigylcerides and also...

Behavioral Cardiology - Where the Heart and Head Meet

While this case is somewhat extreme and unusual, it is not uncommon. It typifies an unusual dilemma in current cardiovascular (CV)...

Cardiac Late Effects and Prevention Strategies for Children Treated with Anthracyclines

Mortality from anthracycline-induced cardiac failure is substantial, with some large studies reporting rates higher than 20%. 4,5 A study of 474...

Cardiac Rehabilitation Update 2008—Biological, Psychological, and Clinical Benefits

Biological Effects of Cardiac Rehabilitation and Exercise TrainingThe numerous benefits of formal CRET programs have been reviewed in detail...

Cardiac Rehabilitation, An Effective and Comprehensive but Underutilized Program to Reduce Cardiovascular Risk in Patients

CR - Much More Than Exercise or an Exercise Training ProgramCR is a comprehensive secondary prevention program that currently includes baseline and...

Cardiovascular Disease Risk Prevention Across Europe

The concept of assessing multiple risk factors concurrently is referred to as total CVD risk, expressed as absolute risk within a defined time...

Cardiovascular Risk Management – Efficacy of Manidipine in Hypertension and Beyond

Recent results from large randomised studies have shown reductions in CV mortality and morbidity in patients with hypertension treated with calcium...

Cerebrovascular Protection by New Antihypertensive Drugs - Focus on RAS Blocking Agents in Stroke Prevention

High blood pressure is one of the most common and powerful contributing factors to stroke and hypertensive patients have a four-fold increased risk...

Clinical Benefits of Inhibition of Cholesterol Absorption for Japanese Patients with Dyslipidaemia

Cholesterol Levels and Coronary Heart Disease RiskDisorders of lipoprotein metabolism, especially elevated low-density lipoprotein (LDL) cholesterol...

Cocoa Flavanols and Cardiovascular Health

Dietary FlavanolIn take and Coronary Heart DiseaseMany population-based studies have used dietary surveys to estimate total flavonoid intake or...

Cocoa Flavonols and Cardiovascular Risk

My own interest in the Kuna arose from an unusual start. I was funded by the National Institutes of Health (NIH) to study the genetics of...

Detection of Ischemia in Patients with Asymptomatic Diabetics

Asymptomatic myocardial ischemia is frequently found in individuals with known CAD, even in individuals without DM, and is associated with a poorer...

Detection of non-ST-elevation myocardial infarction and unstable angina in the acute setting: meta-analysis of diagnostic performance of multi-detector computed tomographic angiography

MethodsA Pubmed and manual search of the literature published between January 2000 and June 2007 was performed. Studies were included that compared...

Direct Renin Inhibition with Focus on Aliskiren and Cardiovascular Outcome Studies

ACE inhibitors and ARBs mediate their effects on the renin system by blocking the synthesis and actions of angiotensin (Ang) II (the major effector...

Do Childhood Risk Factors Affect Arterial Structure and Function?

In the last few years it has become apparent that risk factors can begin in childhood and start to affect arterial structure and function even in the...

Early, Optimal Blood Pressure Control for High-risk Patients

Hypertension Management in DiabetesHypertension in diabetes is one of the most widespread, substantial and treatable CV risk factors of importance in...

Effect of Pioglitazone Compared with Glimepiride on Carotid Intima-media Thickness in Type 2 Diabetes

Patients with type 2 diabetes mellitus (DM) have a marked increase in the risk of myocardial infarction (MI), and a substantially worse prognosis...