Articles

An Update on Carotid Stent Trials and Perspectives

Strokes are frequently devastating events with potentially fatal complications and significant disability, resulting in a major impact on the...

An Update on Patent Foramen Ovale Closure

As an intra-cardiac right-to-left shunt, the patent foramen ovale (PFO) has gained attention over the last two decades because of its potential...

Anaemia in Patients with Diabetic Nephropathy - Prevalence, Causes and Clinical Consequences

The poor prognosis is based on the excessively high cardiovascular morbidity and mortality of these patients whose cause cannot be explained merely...

Angiotensin-receptor Blocker Therapy - Chronic Kidney Disease and Diabetes

Incidence and prevalence counts for ESRD in the US are expected to increase by 44% and 85%, respectively, from 2000 to 2015. In kind, the proportion...

Beyond the Apnea-Hypopnea Index-Prognostic Value of Other Elements of Polysomnography to Describe Sleep-disordered Breathing in Heart Failure

A growing appreciation of the prevalence of sleep breathing disorders, especially as comorbidities of disease syndromes such as chronic heart...

Cadiovascular Risk Factors in Metabolic Syndrome—Impact of Insulin Resistance on Lipids, Hypertension, and the Development of Diabetes and Cardiac Events

MS is closely associated with obesity, which has shown a disturbing increase in prevalence, both in the US and worldwide, creating an unprecedented...

Cardiac Imaging for Assessment of Left Ventricular Thrombus

Accurate detection of left ventricular (LV) thrombus affects clinical outcomes and therapeutic management, as thrombus provides a substrate for...

Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes

Background Cardiovascular disease (CVD) is the leading cause of mortality associated with dysglycaemia. Type 2 diabetes accounts for almost one in...

Cardiovascular Disease Risk Management in Diabetes – The Implications of the REALITY Asia Study

The World Health Organization (WHO) projects that by 2030 more than half of diabetes sufferers in the world will live in Asia, and diabetes is set to...

Carotid Endarterectomy versus Endovascular Stent Placement as Therapy for Symptomatic Carotid Artery Disease

Stroke-related morbidity and mortality remain unacceptably high. Recent estimates suggest that it accounts for approximately one out of every 17...

Clinical Implications of the SYNTAX Study

Coronary artery disease (CAD) is the predominant cause of heart disease and the leading cause of death worldwide. In recent decades revolutionary...

Detection of Silent Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes Mellitus

Diabetes is considered a ‘coronary artery disease (CAD) equivalent’ because patients with diabetes without known CAD have a similar...

Developments in 3D Echocardiography

2D echocardiography (2DE) is a common diagnostic and treatment planning tool in clinical cardiology, especially for the assessment of left...

Developments in Endovascular Abdominal Aortic Aneurysm Treatment

Since its inception in the early 1990s, endovascular repair (EVR) of aneurysms has been subjected to analysis in several randomised ontrolled...

Drug Interactions in Pulmonary Arterial Hypertension and Their Implications

Pulmonary arterial hypertension (PAH) has an estimated prevalence of 15–25 cases/million population.1This chronic, progressive diseaseis defined by...

Drug-eluting Stents-Issues and Developments

Drug-eluting stents (DES) have revolutionized the field of interventional cardiology. The US Food and Drug Administration (FDA) is expecting that the...

Healthy Hearts - a community-based primary prevention programme to reduce coronary heart disease

BackgroundA case can be made for identifying ‘at risk’ individuals, particularly over 45 years of age and for providing them with advice on...

Hypertension and Diabetes Mellitus

Subjects with diabetes are at about 60% increased risk of early mortality. The age-adjusted relative risk of death due to cardiovascular events in...

Iodinated Contrast Media – A Safety Review

The rapid development of percutaneous coronary and peripheral vascular interventional technologies, as well as non-invasive computed tomography...

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