Articles
Aliskiren - Clinical Benefits in the Management of Hypertension
The renin system has a key role in controlling BP.6 Renin, a proteinase enzyme synthesised by the kidney, catalyses the conversion of angiotensinogen...
Amlodipine in the Prevention and Treatment of Cardiovascular Disease
Calcium channel blockers are divided into three classes, the most popular of which are the dihydropyridines. There is more evidence from clinical...
An Update on Hypertension among African-Americans
Epidemiology The rates of hypertension in various populations of African ancestry have geographical variances related to high sodium intake, low...
Angiogenesis Inhibitors and Hypertension
Vascular Endothelial Growth Factor and Blood PressureVascular endothelial growth factor (VEGF) antagonists (or angiogenesis inhibitors) can now be...
Angiotensin-receptor Blocker Therapy - Chronic Kidney Disease and Diabetes
Incidence and prevalence counts for ESRD in the US are expected to increase by 44% and 85%, respectively, from 2000 to 2015. In kind, the proportion...
Cadiovascular Risk Factors in Metabolic Syndrome—Impact of Insulin Resistance on Lipids, Hypertension, and the Development of Diabetes and Cardiac Events
MS is closely associated with obesity, which has shown a disturbing increase in prevalence, both in the US and worldwide, creating an unprecedented...
Cerebrovascular Protection by New Antihypertensive Drugs - Focus on RAS Blocking Agents in Stroke Prevention
High blood pressure is one of the most common and powerful contributing factors to stroke and hypertensive patients have a four-fold increased risk...
Chronobiology and Chronotherapeutics - Possible Strategy for Hypertension and Ischemic Heart Disease
The endocrine system provides many examples illustrating chronobiology. It is the monthly alteration in hormones that initiates menses. The timing of...
Cost-effectiveness of Gadofosveset in the Management of Patients with Symptomatic Peripheral Arterial Occlusive Disease
Both non-invasive and invasive diagnostic procedures are used to confirm the diagnosis of PAOD and to decide on the best method of patient management...
Developments in the Treatment of Hypertension
Increasing Burden of Hypertension WorldwideThe incidence of HT is rising worldwide due to common environmentalfactors. These include excessive...
Direct Renin Inhibitors in Hypertension - Outlook for End Organ Protection
The clinical significance of hypertension stems from the increased risk of end organ damage due to elevated blood pressure (BP) (see Figure 1)....
Does the aldosterone: renin ratio predict the efficacy of spironolactone over bendroflumethiazide in hypertension? A clinical trial protocol for RENALDO (RENin-ALDOsterone) study
BackgroundEpidemiologyOne approach to more effective antihypertensive control would be to target aldosterone antagonists towardspatients in whom...
Healthy Hearts - a community-based primary prevention programme to reduce coronary heart disease
BackgroundA case can be made for identifying ‘at risk’ individuals, particularly over 45 years of age and for providing them with advice on...
Hypertension and Cardiovascular Risk
The optimum level of blood pressure remains open to debate. Epidemiological evidence suggests that blood pressure below 120mmHg is least likely to be...
Hypertension, New Insights and Implications for Management
It is therefore no longer a question of whether to treat hypertension, but more a question of who should be treated and how it should be treated. The...
New Management Strategies for the Hypertensive Patient - from the Disease to the Patient
Today, a remarkable number of antihypertensive drug classes with robust scientific evidence of long-term efficacy and safety are available on the...
News Round Up from AHA Scientific Sessions 2008 - November 10th
Implantable Defibrillators, Pacemakers Affected By MP3 Headphones10 Nov 2008Headphones for MP3 players placed within an inch of pacemakers and...
Reducing the Threat of Vascular Disease in Patients with Hypertension and Hyperlipidemia by Addressing Poor Adherence
Because poor adherence to antihypertensive and lipid-lowering therapy is the norm, it is incumbent upon the physician to work closely with the...
Stenting of Hypoplastic Aortic Segments with Mild Pressure Gradients and Arterial Hypertension
Arterial hypertension is a slow killer. A severe coarctation presenting in the neonatal period is frequently associated with hypoplasia of the aortic...
