Articles
Advances in the Invasive Diagnosis and Treatment of Vulnerable Coronary Plaques
This article describes the relationship between histopathological assessment and in vivo investigations in patients with vulnerable plaques....
Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis
ResultsWhereas the Con diet did not induce early atherosclerosis, the LC diet did so but only mildly, and the HC diet induced it very strongly. With...
Cardiovascular Risk Assessment and Primary Prevention in the Era of Plaque Imaging
According to the Framingham score, seven major independent risk factors for premature CAD have been identified: cigarette smoking,...
Diabetes, gender, and left ventricular structure in African-Americans: the atherosclerosis risk in communities study
Methods We studied 514 male and 965 female African-Americans 51 to 70 years old, in whom echocardiographic left ventricular mass measurements were...
Effects of Reconstituted High-density Lipoprotein Infusions on Coronary Atherosclerosis
While these therapies have proved effective for millions of patients, atherosclerotic cardiovascular disease is still a major contributor to global...
Emerging Role of Inflammatory Biomarkers in Cardiovascular Risk Assessment
Currently, C-reactive protein (CRP), the classical acute-phase protein, seems to be the marker of choice for the clinical situation. However, there...
Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis
The relationship of EL to variation in lipoprotein concentrations and atherosclerosis in humans has not been reported. Several genetic association...
Gene transfer of wild-type apoA-I and apoA-I Milano reduce atherosclerosis to a similar extent
Methods and results Vectors based on AAV serotype 8 (AAV2.8) encoding wtApoA-I, ApoA-IM or green fluorescent protein (GFP) as control were...
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study
Methods Over 100,000 single nucleotide polymorphisms (SNPs) were genotyped (Human 100K GeneChip, Affymetrix) in 1345 subjects from 310 families. We...
Healthy Hearts - a community-based primary prevention programme to reduce coronary heart disease
BackgroundA case can be made for identifying ‘at risk’ individuals, particularly over 45 years of age and for providing them with advice on...
Homocysteine
The advent of simple assays has changed homocysteine measurement from a research tool into a standard and routine clinical test. The following...
Homocysteine, the New Marker of Disease Risk - An Overview
The One-carbon Metabolism Homocysteine is an intermediate product of the one-carbon metabolism. All homocysteine found in mammals is formed during...
Inflammation in Arterial Disease
Clinical Studies All of the clinical manifestations of atherosclerosis have traditionally been associated with inflammation of the plaque. Acute...
News Round Up from AHA Scientific Sessions 2008 - November 10th
Implantable Defibrillators, Pacemakers Affected By MP3 Headphones10 Nov 2008Headphones for MP3 players placed within an inch of pacemakers and...
Plaque Vulnerability and Related Coronary Event Prediction by Virtual Histology
Rapidly accumulating clinical data suggest that a search to identify a single vulnerable plaque to guide local therapy may seriously underestimate...
Relative risk for cardiovascular atherosclerotic events after
BackgroundSmoking is one of the most important risk factors for disease, particularly for lung, and cardiovascular disease(CVD) 1. In many studies...
The Adventitia - The New Frontier in Coronary Atherosclerosis Imaging
The adventitia would appear to be an important element to be taken into account in the understanding and study of human atherosclerosis, with a...
The association of the ankle-brachial index with incident coronary heart disease: the Atherosclerosis Risk In Communities (ARIC)
Methods The ABI was measured in 12186 white and African American men and women in the Atherosclerosis Risk in Communities Study in 1987–89. Fatal...
The effects of second-hand smoke on biological processes important in atherogenesis
Many factors can lead to initiation of atherosclerosis. In the Framingham heart study,10-12 the best-known prospective investigation that established...
The Emerging Role of Flavonoid-Rich Cocoa and Chocolate in Cardiovascular Health and Disease
Epidemiological studies suggest flavonoid-rich diets high in fruits and/or vegetables reduce the risk of coronary heart disease. (2-4) A recent...
